STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PTDSS1Phosphatidylserine synthase 1. (599 aa)    
Predicted Functional Partners:
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 
 0.983
PEMT
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
   
 
 0.972
PTDSS2
Phosphatidylserine synthase 2.
  
 
0.928
PLA2G3
Phospholipase A2 group III.
     
 0.925
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
   
 
 0.918
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.917
MBOAT2
Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family.
     
 0.907
LPCAT3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
     
 0.907
PLA1A
Phospholipase A1 member A.
     
 0.905
PLA2G4F
Phospholipase A2.
     
 0.903
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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