STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL8Kelch like family member 8. (618 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.954
TRAM1L1
Translocating chain-associated membrane protein; Belongs to the TRAM family.
      
 0.869
SLC25A36
Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.869
BNIPL
BCL2 interacting protein like.
      
 0.832
VCPIP1
Valosin containing protein interacting protein 1.
   
 
 0.816
GPR160
G protein-coupled receptor 160.
      
 0.785
SNRNP70
Small nuclear ribonucleoprotein U1 subunit 70.
   
   0.784
KLHL17
Kelch like family member 17.
    
   0.674
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
      
 0.625
APPBP2
Amyloid beta precursor protein binding protein 2.
    
 0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.