STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC478844Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)    
Predicted Functional Partners:
CSTB
Cystatin B.
      
 0.827
FAM3C
Family with sequence similarity 3 member C.
      
 0.691
C5
Complement C5.
    
 0.621
SPINK1
Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity).
   
 
 0.532
ENSCAFP00000054705
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
    0.527
LOC106558389
Profilin; Belongs to the profilin family.
      
 0.524
ELANE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
    0.524
J9NXN6_CANLF
Uncharacterized protein; Belongs to the peptidase S1 family.
  
    0.519
PFN4
Profilin; Belongs to the profilin family.
      
 0.518
PFN2
Profilin; Belongs to the profilin family.
      
 0.516
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.