AKTIP protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AKTIP

AKT interacting protein. (293 aa)

Predicted Functional Partners:

HOOK3

0.980

FAM160A1

0.977

FAM160A2

0.963

HOOK2

0.933

HOOK1

0.891

TNFSF13B

0.837

FAM160B1

0.693

EDA

0.670

EGFR

0.573

RBM33

0.566

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKTIP	EDA	ENSCAFP00000013969	ENSCAFP00000037326	AKT interacting protein.	Ectodysplasin A isoform EDA-A2; Belongs to the tumor necrosis factor family.	0.670
AKTIP	EGFR	ENSCAFP00000013969	ENSCAFP00000005164	AKT interacting protein.	Receptor protein-tyrosine kinase.	0.573
AKTIP	FAM160A1	ENSCAFP00000013969	ENSCAFP00000011911	AKT interacting protein.	Family with sequence similarity 160 member A1.	0.977
AKTIP	FAM160A2	ENSCAFP00000013969	ENSCAFP00000009571	AKT interacting protein.	Family with sequence similarity 160 member A2.	0.963
AKTIP	FAM160B1	ENSCAFP00000013969	ENSCAFP00000017136	AKT interacting protein.	Family with sequence similarity 160 member B1.	0.693
AKTIP	HOOK1	ENSCAFP00000013969	ENSCAFP00000027841	AKT interacting protein.	Hook microtubule tethering protein 1.	0.891
AKTIP	HOOK2	ENSCAFP00000013969	ENSCAFP00000060969	AKT interacting protein.	Hook microtubule tethering protein 2.	0.933
AKTIP	HOOK3	ENSCAFP00000013969	ENSCAFP00000008062	AKT interacting protein.	Hook microtubule tethering protein 3.	0.980
AKTIP	RBM33	ENSCAFP00000013969	ENSCAFP00000037965	AKT interacting protein.	RNA binding motif protein 33.	0.566
AKTIP	TNFSF13B	ENSCAFP00000013969	ENSCAFP00000035956	AKT interacting protein.	Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.	0.837
EDA	AKTIP	ENSCAFP00000037326	ENSCAFP00000013969	Ectodysplasin A isoform EDA-A2; Belongs to the tumor necrosis factor family.	AKT interacting protein.	0.670
EGFR	AKTIP	ENSCAFP00000005164	ENSCAFP00000013969	Receptor protein-tyrosine kinase.	AKT interacting protein.	0.573
FAM160A1	AKTIP	ENSCAFP00000011911	ENSCAFP00000013969	Family with sequence similarity 160 member A1.	AKT interacting protein.	0.977
FAM160A1	FAM160B1	ENSCAFP00000011911	ENSCAFP00000017136	Family with sequence similarity 160 member A1.	Family with sequence similarity 160 member B1.	0.681
FAM160A1	HOOK1	ENSCAFP00000011911	ENSCAFP00000027841	Family with sequence similarity 160 member A1.	Hook microtubule tethering protein 1.	0.728
FAM160A1	HOOK2	ENSCAFP00000011911	ENSCAFP00000060969	Family with sequence similarity 160 member A1.	Hook microtubule tethering protein 2.	0.824
FAM160A1	HOOK3	ENSCAFP00000011911	ENSCAFP00000008062	Family with sequence similarity 160 member A1.	Hook microtubule tethering protein 3.	0.975
FAM160A1	TNFSF13B	ENSCAFP00000011911	ENSCAFP00000035956	Family with sequence similarity 160 member A1.	Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.	0.675
FAM160A2	AKTIP	ENSCAFP00000009571	ENSCAFP00000013969	Family with sequence similarity 160 member A2.	AKT interacting protein.	0.963
FAM160A2	HOOK1	ENSCAFP00000009571	ENSCAFP00000027841	Family with sequence similarity 160 member A2.	Hook microtubule tethering protein 1.	0.728