STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF7PHD finger protein 7. (383 aa)    
Predicted Functional Partners:
TCEAL1
Transcription elongation factor A like 1.
    
   0.815
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 
 0.798
CDK16
Ubiquitin carboxyl-terminal hydrolase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys- 63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys- 33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA brea [...]
    
 
 0.652
NUTM1
Uncharacterized protein.
   
 0.631
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.629
ODF1
Outer dense fiber of sperm tails 1.
   
  
 0.621
MEIKIN
Meiotic kinetochore factor.
    
 
 0.616
PNLDC1
PARN like, ribonuclease domain containing 1.
   
  
 0.606
ADAD2
Adenosine deaminase domain containing 2.
      
 0.606
ARRDC5
Arrestin domain containing 5.
   
 
 0.606
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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