RTF1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RTF1

RTF1 homolog, Paf1/RNA polymerase II complex component. (714 aa)

Predicted Functional Partners:

CTR9

0.999

CDC73

0.998

PAF1

0.997

LEO1

0.994

WDR61

0.973

ENSCAFP00000062903

0.973

ENSCAFP00000066299

0.973

CHD1

0.906

SUPT16H

0.901

SSRP1

0.889

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CHD1	ENSCAFP00000061651	ENSCAFP00000011432	Cell division cycle 73.	Chromodomain helicase DNA binding protein 1.	0.665
CDC73	CTR9	ENSCAFP00000061651	ENSCAFP00000011354	Cell division cycle 73.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	ENSCAFP00000062903	ENSCAFP00000061651	ENSCAFP00000062903	Cell division cycle 73.	WD_REPEATS_REGION domain-containing protein.	0.977
CDC73	ENSCAFP00000066299	ENSCAFP00000061651	ENSCAFP00000066299	Cell division cycle 73.	Uncharacterized protein.	0.977
CDC73	LEO1	ENSCAFP00000061651	ENSCAFP00000044474	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	PAF1	ENSCAFP00000061651	ENSCAFP00000060456	Cell division cycle 73.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.996
CDC73	RTF1	ENSCAFP00000061651	ENSCAFP00000014037	Cell division cycle 73.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	SSRP1	ENSCAFP00000061651	ENSCAFP00000011769	Cell division cycle 73.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.870
CDC73	SUPT16H	ENSCAFP00000061651	ENSCAFP00000008366	Cell division cycle 73.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.939
CDC73	WDR61	ENSCAFP00000061651	ENSCAFP00000020974	Cell division cycle 73.	WD repeat domain 61.	0.977
CHD1	CDC73	ENSCAFP00000011432	ENSCAFP00000061651	Chromodomain helicase DNA binding protein 1.	Cell division cycle 73.	0.665
CHD1	CTR9	ENSCAFP00000011432	ENSCAFP00000011354	Chromodomain helicase DNA binding protein 1.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.742
CHD1	LEO1	ENSCAFP00000011432	ENSCAFP00000044474	Chromodomain helicase DNA binding protein 1.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.602
CHD1	PAF1	ENSCAFP00000011432	ENSCAFP00000060456	Chromodomain helicase DNA binding protein 1.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.829
CHD1	RTF1	ENSCAFP00000011432	ENSCAFP00000014037	Chromodomain helicase DNA binding protein 1.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.906
CHD1	SSRP1	ENSCAFP00000011432	ENSCAFP00000011769	Chromodomain helicase DNA binding protein 1.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.842
CHD1	SUPT16H	ENSCAFP00000011432	ENSCAFP00000008366	Chromodomain helicase DNA binding protein 1.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.593
CTR9	CDC73	ENSCAFP00000011354	ENSCAFP00000061651	CTR9 homolog, Paf1/RNA polymerase II complex component.	Cell division cycle 73.	0.998
CTR9	CHD1	ENSCAFP00000011354	ENSCAFP00000011432	CTR9 homolog, Paf1/RNA polymerase II complex component.	Chromodomain helicase DNA binding protein 1.	0.742
CTR9	ENSCAFP00000062903	ENSCAFP00000011354	ENSCAFP00000062903	CTR9 homolog, Paf1/RNA polymerase II complex component.	WD_REPEATS_REGION domain-containing protein.	0.980