STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IMPG2Interphotoreceptor matrix proteoglycan 2. (1234 aa)    
Predicted Functional Partners:
FAM161A
FAM161 centrosomal protein A.
      
 0.888
CEP97
Centrosomal protein 97.
    
 
 0.859
CEP78
Centrosomal protein 78.
   
 
 0.818
CEP19
Centrosomal protein 19.
      
 0.810
OVOL2
Ovo like zinc finger 2.
      
 0.801
CEP164
Centrosomal protein 164.
    
 0.708
CEP250
Centrosomal protein 250.
   
 0.634
PITX1
Homeobox protein.
      
 0.532
CRX
Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.
      
 0.518
CEP290
Centrosomal protein 290.
    
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.