STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBSPIntegrin binding sialoprotein. (319 aa)    
Predicted Functional Partners:
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 
 0.932
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.907
DMP1
Dentin matrix acidic phosphoprotein 1.
   
  
 0.756
MEPE
Matrix extracellular phosphoglycoprotein.
   
  
 0.740
RUNX2
RUNX family transcription factor 2.
   
  
 0.736
ALPL
Alkaline phosphatase.
   
  
 0.724
FAM184B
Family with sequence similarity 184 member B.
   
 
 0.701
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
     
 0.691
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
     
 0.690
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
     
 0.690
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.