IBSP protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

IBSP

Integrin binding sialoprotein. (319 aa)

Predicted Functional Partners:

ITGB3

0.964

ITGAV

0.897

ITGB5

0.889

ITGB8

0.884

ITGA6

0.881

DMP1

0.845

ITGB1

0.839

RUNX2

0.828

ITGA8

0.824

ITGB7

0.822

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMP1	IBSP	ENSCAFP00000014035	ENSCAFP00000014046	Dentin matrix acidic phosphoprotein 1.	Integrin binding sialoprotein.	0.845
DMP1	ITGA8	ENSCAFP00000014035	ENSCAFP00000006951	Dentin matrix acidic phosphoprotein 1.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.569
DMP1	ITGAV	ENSCAFP00000014035	ENSCAFP00000050990	Dentin matrix acidic phosphoprotein 1.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.882
DMP1	ITGB1	ENSCAFP00000014035	ENSCAFP00000005722	Dentin matrix acidic phosphoprotein 1.	Integrin beta; Belongs to the integrin beta chain family.	0.707
DMP1	ITGB3	ENSCAFP00000014035	ENSCAFP00000032511	Dentin matrix acidic phosphoprotein 1.	Integrin beta; Belongs to the integrin beta chain family.	0.963
DMP1	ITGB5	ENSCAFP00000014035	ENSCAFP00000040050	Dentin matrix acidic phosphoprotein 1.	Integrin beta; Belongs to the integrin beta chain family.	0.710
DMP1	ITGB7	ENSCAFP00000014035	ENSCAFP00000054149	Dentin matrix acidic phosphoprotein 1.	Integrin beta; Belongs to the integrin beta chain family.	0.534
DMP1	RUNX2	ENSCAFP00000014035	ENSCAFP00000042290	Dentin matrix acidic phosphoprotein 1.	RUNX family transcription factor 2.	0.591
IBSP	DMP1	ENSCAFP00000014046	ENSCAFP00000014035	Integrin binding sialoprotein.	Dentin matrix acidic phosphoprotein 1.	0.845
IBSP	ITGA6	ENSCAFP00000014046	ENSCAFP00000054417	Integrin binding sialoprotein.	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	0.881
IBSP	ITGA8	ENSCAFP00000014046	ENSCAFP00000006951	Integrin binding sialoprotein.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.824
IBSP	ITGAV	ENSCAFP00000014046	ENSCAFP00000050990	Integrin binding sialoprotein.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.897
IBSP	ITGB1	ENSCAFP00000014046	ENSCAFP00000005722	Integrin binding sialoprotein.	Integrin beta; Belongs to the integrin beta chain family.	0.839
IBSP	ITGB3	ENSCAFP00000014046	ENSCAFP00000032511	Integrin binding sialoprotein.	Integrin beta; Belongs to the integrin beta chain family.	0.964
IBSP	ITGB5	ENSCAFP00000014046	ENSCAFP00000040050	Integrin binding sialoprotein.	Integrin beta; Belongs to the integrin beta chain family.	0.889
IBSP	ITGB7	ENSCAFP00000014046	ENSCAFP00000054149	Integrin binding sialoprotein.	Integrin beta; Belongs to the integrin beta chain family.	0.822
IBSP	ITGB8	ENSCAFP00000014046	ENSCAFP00000058857	Integrin binding sialoprotein.	Integrin beta; Belongs to the integrin beta chain family.	0.884
IBSP	RUNX2	ENSCAFP00000014046	ENSCAFP00000042290	Integrin binding sialoprotein.	RUNX family transcription factor 2.	0.828
ITGA6	IBSP	ENSCAFP00000054417	ENSCAFP00000014046	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	Integrin binding sialoprotein.	0.881
ITGA6	ITGA8	ENSCAFP00000054417	ENSCAFP00000006951	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.820