STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (323 aa)    
Predicted Functional Partners:
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.929
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.927
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
 
 0.922
P4HB
Protein disulfide-isomerase.
   
 0.912
PDIA4
Protein disulfide isomerase family A member 4; Belongs to the protein disulfide isomerase family.
   
 0.910
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 
 0.895
PRDX4
Peroxiredoxin 4.
   
 
 0.870
ERP29
Endoplasmic reticulum protein 29.
   
 0.863
PDIA2
Protein disulfide isomerase family A member 2.
   
 0.858
PDIA3
Protein disulfide-isomerase.
   
 0.806
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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