STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCNPPEST proteolytic signal containing nuclear protein. (174 aa)    
Predicted Functional Partners:
KLHL2
Kelch like family member 2.
      
 0.858
TULP4
Tubby like protein 4; Belongs to the TUB family.
      
 0.844
UHRF2
Ubiquitin like with PHD and ring finger domains 2.
    
 
 0.834
GRIPAP1
GRIP1 associated protein 1.
    
   0.811
UBE3C
Ubiquitin protein ligase E3C.
      
 0.801
OSTN
Osteocrin.
    
   0.712
MYCBP2
MYC binding protein 2.
      
 0.697
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
      
 0.692
UHRF1
Ubiquitin like with PHD and ring finger domains 1.
    
 
 0.641
ABI3BP
ABI family member 3 binding protein.
      
 0.621
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.