STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCNPPEST proteolytic signal containing nuclear protein. (174 aa)    
Predicted Functional Partners:
TULP4
Tubby like protein 4; Belongs to the TUB family.
      
 0.837
ABI3BP
ABI family member 3 binding protein.
      
 0.802
KLHL2
Kelch like family member 2.
   
  
 0.771
UBE3C
Ubiquitin protein ligase E3C.
   
  
 0.734
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
      
 0.711
UHRF2
Ubiquitin like with PHD and ring finger domains 2.
   
 
 0.710
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
      
 0.648
MYCBP2
MYC binding protein 2.
      
 0.643
LBR
Lamin B receptor.
   
  
 0.561
POLI
DNA polymerase iota.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.