STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (874 aa)    
Predicted Functional Partners:
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
    
 0.884
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
   
 
 0.833
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.793
ARL13B
ADP ribosylation factor like GTPase 13B.
      
 0.778
IFT20
Intraflagellar transport 20.
   
  
 0.755
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
   
 
 0.701
IFT140
Uncharacterized protein.
      
 0.689
PKDREJ
Polycystin family receptor for egg jelly.
   
 
0.670
IBSP
Integrin binding sialoprotein.
    
 
 0.653
ARF4
ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.650
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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