| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBFB | CDK6 | ENSCAFP00000030239 | ENSCAFP00000002945 | Core-binding factor subunit beta. | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. | 0.702 |
| CBFB | FOXP3 | ENSCAFP00000030239 | ENSCAFP00000023435 | Core-binding factor subunit beta. | Forkhead box P3. | 0.658 |
| CBFB | HDAC1 | ENSCAFP00000030239 | ENSCAFP00000036819 | Core-binding factor subunit beta. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.516 |
| CBFB | RUNX1 | ENSCAFP00000030239 | ENSCAFP00000014111 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.979 |
| CBFB | TAL1 | ENSCAFP00000030239 | ENSCAFP00000005977 | Core-binding factor subunit beta. | TAL bHLH transcription factor 1, erythroid differentiation factor. | 0.613 |
| CDK6 | CBFB | ENSCAFP00000002945 | ENSCAFP00000030239 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. | Core-binding factor subunit beta. | 0.702 |
| CDK6 | CEBPA | ENSCAFP00000002945 | ENSCAFP00000011002 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. | BZIP domain-containing protein. | 0.404 |
| CDK6 | RUNX1 | ENSCAFP00000002945 | ENSCAFP00000014111 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.855 |
| CEBPA | CDK6 | ENSCAFP00000011002 | ENSCAFP00000002945 | BZIP domain-containing protein. | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. | 0.404 |
| CEBPA | HDAC1 | ENSCAFP00000011002 | ENSCAFP00000036819 | BZIP domain-containing protein. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.469 |
| CEBPA | RUNX1 | ENSCAFP00000011002 | ENSCAFP00000014111 | BZIP domain-containing protein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.884 |
| CEBPA | SPI1 | ENSCAFP00000011002 | ENSCAFP00000012822 | BZIP domain-containing protein. | Spi-1 proto-oncogene. | 0.711 |
| CSF1R | PTPN11 | ENSCAFP00000053521 | ENSCAFP00000013074 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.796 |
| CSF1R | RUNX1 | ENSCAFP00000053521 | ENSCAFP00000014111 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.846 |
| CSF1R | SPI1 | ENSCAFP00000053521 | ENSCAFP00000012822 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Spi-1 proto-oncogene. | 0.970 |
| FOXP3 | CBFB | ENSCAFP00000023435 | ENSCAFP00000030239 | Forkhead box P3. | Core-binding factor subunit beta. | 0.658 |
| FOXP3 | HDAC1 | ENSCAFP00000023435 | ENSCAFP00000036819 | Forkhead box P3. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.529 |
| FOXP3 | RUNX1 | ENSCAFP00000023435 | ENSCAFP00000014111 | Forkhead box P3. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.935 |
| HDAC1 | CBFB | ENSCAFP00000036819 | ENSCAFP00000030239 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Core-binding factor subunit beta. | 0.516 |
| HDAC1 | CEBPA | ENSCAFP00000036819 | ENSCAFP00000011002 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | BZIP domain-containing protein. | 0.469 |
