NELL2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

NELL2

Neural EGFL like 2. (864 aa)

Predicted Functional Partners:

C3H4orf48

0.629

FRMPD3

0.606

ANKRD6

0.592

MTMR10

0.555

USP20

0.551

NDUFAF6

0.542

LOC100856270

0.541

DBR1

0.508

VPS13A

0.508

GPM6A

0.477

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD6	NELL2	ENSCAFP00000060941	ENSCAFP00000014126	Ankyrin repeat domain 6.	Neural EGFL like 2.	0.592
C3H4orf48	NELL2	ENSCAFP00000052456	ENSCAFP00000014126	Uncharacterized protein.	Neural EGFL like 2.	0.629
DBR1	NELL2	ENSCAFP00000011147	ENSCAFP00000014126	Debranching RNA lariats 1.	Neural EGFL like 2.	0.508
DBR1	VPS13A	ENSCAFP00000011147	ENSCAFP00000039659	Debranching RNA lariats 1.	Vacuolar protein sorting 13 homolog A.	0.676
FRMPD3	NELL2	ENSCAFP00000026548	ENSCAFP00000014126	FERM and PDZ domain containing 3.	Neural EGFL like 2.	0.606
FRMPD3	USP20	ENSCAFP00000026548	ENSCAFP00000029601	FERM and PDZ domain containing 3.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.822
GPM6A	MTMR10	ENSCAFP00000012498	ENSCAFP00000015199	Glycoprotein M6A.	Myotubularin related protein 10.	0.630
GPM6A	NELL2	ENSCAFP00000012498	ENSCAFP00000014126	Glycoprotein M6A.	Neural EGFL like 2.	0.477
LOC100856270	NELL2	ENSCAFP00000019191	ENSCAFP00000014126	Ig-like domain-containing protein.	Neural EGFL like 2.	0.541
MTMR10	GPM6A	ENSCAFP00000015199	ENSCAFP00000012498	Myotubularin related protein 10.	Glycoprotein M6A.	0.630
MTMR10	NELL2	ENSCAFP00000015199	ENSCAFP00000014126	Myotubularin related protein 10.	Neural EGFL like 2.	0.555
NDUFAF6	NELL2	ENSCAFP00000054246	ENSCAFP00000014126	NADH:ubiquinone oxidoreductase complex assembly factor 6.	Neural EGFL like 2.	0.542
NELL2	ANKRD6	ENSCAFP00000014126	ENSCAFP00000060941	Neural EGFL like 2.	Ankyrin repeat domain 6.	0.592
NELL2	C3H4orf48	ENSCAFP00000014126	ENSCAFP00000052456	Neural EGFL like 2.	Uncharacterized protein.	0.629
NELL2	DBR1	ENSCAFP00000014126	ENSCAFP00000011147	Neural EGFL like 2.	Debranching RNA lariats 1.	0.508
NELL2	FRMPD3	ENSCAFP00000014126	ENSCAFP00000026548	Neural EGFL like 2.	FERM and PDZ domain containing 3.	0.606
NELL2	GPM6A	ENSCAFP00000014126	ENSCAFP00000012498	Neural EGFL like 2.	Glycoprotein M6A.	0.477
NELL2	LOC100856270	ENSCAFP00000014126	ENSCAFP00000019191	Neural EGFL like 2.	Ig-like domain-containing protein.	0.541
NELL2	MTMR10	ENSCAFP00000014126	ENSCAFP00000015199	Neural EGFL like 2.	Myotubularin related protein 10.	0.555
NELL2	NDUFAF6	ENSCAFP00000014126	ENSCAFP00000054246	Neural EGFL like 2.	NADH:ubiquinone oxidoreductase complex assembly factor 6.	0.542