STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI3Leucine rich repeat LGI family member 3. (548 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
     
 0.909
ADAM23
ADAM metallopeptidase domain 23.
   
  
 0.860
HSPA12A
Heat shock protein family A (Hsp70) member 12A.
    
 0.783
FNDC3B
Fibronectin type III domain containing 3B.
     
 0.746
ADAM11
ADAM metallopeptidase domain 11.
      
 0.700
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
      
 0.608
FLOT1
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
 
 0.597
PTPRN
Protein tyrosine phosphatase receptor type N.
      
 0.594
PTPRN2
Protein tyrosine phosphatase receptor type N2.
   
  
 0.525
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
   
 
 0.524
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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