STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA6Pleckstrin homology domain containing A6. (1171 aa)    
Predicted Functional Partners:
STAP1
Signal transducing adaptor family member 1.
      
 0.503
IRGQ
Immunity related GTPase Q.
   
  
 0.502
CLEC12B
C-type lectin domain family 12 member B.
      
 0.483
VMO1
Vitelline membrane outer layer 1 homolog.
   
 
 0.481
PPFIA4
PTPRF interacting protein alpha 4.
   
 
 0.468
DLEC1
DLEC1 cilia and flagella associated protein.
    
 
 0.460
GPR155
G protein-coupled receptor 155.
      
 0.457
PPM1J
Protein phosphatase, Mg2+/Mn2+ dependent 1J.
      
 0.457
WDFY4
WDFY family member 4.
      
 0.449
MVB12B
Multivesicular body subunit 12B.
      
 0.449
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.