STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HLCSHolocarboxylase synthetase. (724 aa)    
Predicted Functional Partners:
BTD
Biotinidase.
    
 0.979
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.941
PCCA
Propionyl-CoA carboxylase subunit alpha.
    
 0.922
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
    
 0.919
ACACA
Acetyl-CoA carboxylase alpha.
  
 0.881
PCCB
Propionyl-CoA carboxylase subunit beta.
  
 
 0.880
ACACB
Acetyl-CoA carboxylase beta.
  
 0.878
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
  
 
 0.829
SPATA46
Spermatogenesis associated 46.
    
   0.782
KCNJ6
Potassium voltage-gated channel subfamily J member 6.
      
 0.698
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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