STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RIPPLY3Ripply transcriptional repressor 3. (246 aa)    
Predicted Functional Partners:
CD6
CD6 molecule.
      
 0.614
EP300
E1A binding protein p300.
   
  
 0.536
TBX20
T-box transcription factor 20.
    
 
 0.528
IRX1
Iroquois homeobox 1.
      
 0.481
NEPN
Uncharacterized protein.
      
 0.449
P2RY10
P2Y receptor family member 10.
      
 0.436
TBX2
T-box transcription factor TBX2; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. May be Required for cardiac atrioventricular canal formation (By similarity).
   
  
 0.434
TBX15
T-box transcription factor 15.
    
 
 0.422
TBX18
T-box transcription factor 18.
    
 
 0.422
GDPD1
Glycerophosphodiester phosphodiesterase domain containing 1.
      
 0.410
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.