STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM160B2Family with sequence similarity 160 member B2. (732 aa)    
Predicted Functional Partners:
HMBOX1
Homeobox containing 1.
   
  
 0.858
TMEM109
Transmembrane protein 132A.
      
 0.783
ADAM28
ADAM metallopeptidase domain 28.
      
 0.698
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
      
 0.678
RBM17
RNA binding motif protein 17.
      
 0.671
STMN4
Stathmin 4.
      
 0.661
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
  
 0.612
CISH
Cytokine inducible SH2 containing protein.
      
 0.574
HNRNPK
Heterogeneous nuclear ribonucleoprotein K.
   
  
 0.574
MON1B
MON1 homolog B, secretory trafficking associated.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.