STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINT4Serine peptidase inhibitor, Kunitz type 4. (98 aa)    
Predicted Functional Partners:
WFDC13
WAP four-disulfide core domain 13.
   
 
 0.844
WFDC8
WAP four-disulfide core domain 8.
      
 0.836
WFDC10B
WAP four-disulfide core domain 10B.
      
 0.811
HGFAC
Hepatocyte growth factor activator short chain; Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form; Belongs to the peptidase S1 family.
    
 
 0.754
SPINT2
Uncharacterized protein.
      
 0.750
TP53TG5
TP53 target 5.
      
 0.715
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
      
 0.678
SPINT3
Early lactation protein.
      
 0.678
WFDC3
WAP four-disulfide core domain 3.
      
 0.675
SYS1
Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family.
   
  
 0.585
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.