STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPINT4Serine peptidase inhibitor, Kunitz type 4. (98 aa)    
Predicted Functional Partners:
WFDC8
WAP four-disulfide core domain 8.
      
 0.883
WFDC13
WAP four-disulfide core domain 13.
   
 
 0.845
WFDC10B
WAP four-disulfide core domain 10B.
      
 0.818
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
      
 0.698
SPINT2
Uncharacterized protein.
      
 0.692
LOC102152702
BPTI/Kunitz inhibitor domain-containing protein.
      
 0.692
WFDC3
WAP four-disulfide core domain 3.
      
 0.692
SPINT3
Early lactation protein.
      
 0.688
HGFAC
Hepatocyte growth factor activator short chain; Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form; Belongs to the peptidase S1 family.
    
 
 0.641
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
      
 0.592
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.