STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNTTIP1Deoxynucleotidyltransferase terminal interacting protein 1. (371 aa)    
Predicted Functional Partners:
ELMSAN1
ELM2 and Myb/SANT domain containing 1.
    
 
 0.968
TRERF1
Transcriptional regulating factor 1.
    
 
 0.948
ZNF541
Zinc finger protein 541.
    
 
 0.822
WFDC10B
WAP four-disulfide core domain 10B.
      
 0.789
WFDC13
WAP four-disulfide core domain 13.
      
 0.789
KCTD19
Potassium channel tetramerization domain containing 19.
   
  
 0.784
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.753
HDAC2
Histone deacetylase 2.
   
 
 0.712
NUDC
Nuclear distribution C, dynein complex regulator.
   
  
 0.690
CUL9
Cullin 9; Belongs to the cullin family.
   
  
 0.683
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.