STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLB1L2Beta-galactosidase. (636 aa)    
Predicted Functional Partners:
RNASE13
Ribonuclease A family member 13 (inactive); Belongs to the pancreatic ribonuclease family.
      
 0.875
PATE3
Prostate and testis expressed 3.
      
 0.875
PATE2
Prostate and testis expressed 2.
      
 0.875
PATE1
Prostate and testis expressed 1.
      
 0.875
RPL8
Ribosomal protein L8.
   
  
 0.690
CPVL
Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.
   
 
 0.600
MON1B
MON1 homolog B, secretory trafficking associated.
      
 0.515
DEPDC1
DEP domain containing 1.
   
  
 0.513
RPE65
Retinoid isomerohydrolase; Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-tra [...]
      
 0.505
DEFB121
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.459
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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