STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCM2Glial cells missing transcription factor 2. (506 aa)    
Predicted Functional Partners:
GCM1
Glial cells missing transcription factor 1.
  
 
0.911
FOXN1
Forkhead box N1.
   
 
 0.845
FOXI3
Forkhead box protein I3; Possible transcriptional factor. May play a role in the development of the epithelium of hair and whisker placodes and that of teeth.
   
 
 0.756
PAX1
Paired box 1.
   
  
 0.673
TMEM74
Transmembrane protein 74.
      
 0.646
PAX9
Paired box 9.
   
  
 0.633
CASR
Calcium-sensing receptor.
   
 
 0.618
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).
   
  
 0.596
PKNOX2
PBX/knotted 1 homeobox 2.
   
  
 0.584
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
   
  
 0.573
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.