STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCM2Glial cells missing transcription factor 2. (506 aa)    
Predicted Functional Partners:
GCM1
Glial cells missing transcription factor 1.
     
 0.884
FOXI3
Forkhead box protein I3; Possible transcriptional factor. May play a role in the development of the epithelium of hair and whisker placodes and that of teeth.
   
 
 0.792
CASR
Calcium-sensing receptor.
    
 
 0.779
FHL3
Four and a half LIM domains 3.
    
   0.774
FOXN1
Forkhead box N1.
    
 
 0.770
PAX9
Paired box 9.
      
 0.713
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).
   
 
 0.712
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
      
 0.595
LOC111094819
HSF_DOMAIN domain-containing protein.
    
   0.588
H9GWV1_CANLF
HSF_DOMAIN domain-containing protein.
    
   0.588
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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