STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)    
Predicted Functional Partners:
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.933
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.928
CDC20
Cell division cycle 20.
   
 
 0.927
DLGAP5
DLG associated protein 5.
   
  
 0.926
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.923
CDC20B
Cell division cycle 20B.
   
 
 0.907
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.900
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.892
CDCA3
Cell division cycle associated 3.
   
  
 0.890
PTTG1
Uncharacterized protein.
   
 
 0.888
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.