STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC3HECT and RLD domain containing E3 ubiquitin protein ligase 3. (1050 aa)    
Predicted Functional Partners:
NAP1L5
Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.783
NAP1L3
Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family.
   
  
 0.677
NAP1L2
Nucleosome assembly protein 1 like 2; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.643
ASB4
Ankyrin repeat and SOCS box containing 4.
   
 
 0.639
CHRAC1
Chromatin accessibility complex subunit 1.
   
  
 0.598
PIGY
PIGY upstream reading frame.
   
  
 0.590
TRAPPC9
Trafficking protein particle complex 9.
   
  
 0.584
BLCAP
BLCAP apoptosis inducing factor.
      
 0.576
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.569
DNAJB3
J domain-containing protein.
      
 0.566
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.