STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN3Sidoreflexin. (325 aa)    
Predicted Functional Partners:
CREG2
Cellular repressor of E1A stimulated genes 2; Belongs to the CREG family.
      
 0.818
SREK1IP1
SREK1 interacting protein 1.
      
 0.813
SREK1
Splicing regulatory glutamic acid and lysine rich protein 1.
      
 0.813
ZNF572
Zinc finger protein 572.
      
 0.810
WIPF1
WAS/WASL interacting protein family member 1.
      
 0.741
PMP2
Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.692
FABP9
FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.690
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
   
  
 0.618
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.609
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3.
      
 0.602
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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