STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLX1T cell leukemia homeobox 1. (337 aa)    
Predicted Functional Partners:
TMEM169
Transmembrane protein 169.
      
 0.688
ZIC4
Zic family member 4.
   
 0.622
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
      
 0.570
LHX5
LIM homeobox 5.
    
 
 0.544
PAX2
Paired box 2.
      
 0.542
NUP214
Nucleoporin 214.
      
 0.540
KSR2
Kinase suppressor of ras 2.
    
 
 0.523
LMO1
LIM domain only 1.
    
 
 0.517
LMO2
LIM domain only 2.
    
 
 0.497
SNAI3
Snail family transcriptional repressor 3.
    
 
 0.495
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.