STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPRIN3GPRIN family member 3. (776 aa)    
Predicted Functional Partners:
PPIG
Peptidylprolyl isomerase G.
      
 0.790
SERPINA14
SERPIN domain-containing protein; Belongs to the serpin family.
      
 0.707
CHST11
Carbohydrate sulfotransferase.
      
 0.642
SDCCAG8
Serologically defined colon cancer antigen 8.
      
 0.641
HS3ST2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.569
LIPG
Lipase G, endothelial type.
      
 0.561
RSAD2
Radical S-adenosyl methionine domain containing 2.
      
 0.560
SH3BGRL2
SH3 domain binding glutamate rich protein like 2.
      
 0.519
HS3ST5
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.499
GRIN1
Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
   
  
 0.453
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.