STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (758 aa)    
Predicted Functional Partners:
SLC6A9
Solute carrier family 6 member 9.
  
  
0.895
GLRA1
Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.860
SLC32A1
Solute carrier family 32 member 1.
   
  
 0.796
GLRB
Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.785
GPHN
Gephyrin.
   
  
 0.723
SLC17A6
Solute carrier family 17 member 6.
   
  
 0.702
TECTB
Tectorin beta.
      
 0.691
SLC1A6
Excitatory amino acid transporter 4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which [...]
  
 
 0.642
GPR50
G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.
    
 0.614
TMC2
Transmembrane channel-like protein.
   
  
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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