STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRK2Leucine rich repeat kinase 2. (2527 aa)    
Predicted Functional Partners:
DNM1L
Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.942
CDC37
Cell division cycle 37.
    
 0.934
MSN
Moesin.
    
 
 0.934
STUB1
STIP1 homology and U-box containing protein 1.
    
 
 0.932
MBP
Myelin basic protein.
   
 
 0.932
MAPT
Microtubule-associated protein.
    
 0.908
RAB29
RAB29, member RAS oncogene family.
    
 
 0.902
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
 0.889
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
 
 0.882
EIF4EBP1
Eukaryotic translation initiation factor 4E binding protein 1.
    
 
 0.857
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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