STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (920 aa)    
Predicted Functional Partners:
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4.
    
   0.698
PCDH12
Protocadherin 12.
    
 
 0.593
CADM4
Cell adhesion molecule 4.
      
 0.591
MMP19
Matrix metallopeptidase 19.
    
 
 0.552
ANGPTL6
Angiopoietin like 6.
      
 0.534
USF2
Upstream transcription factor 2, c-fos interacting.
    
 
 0.507
AACS
Transmembrane protein 132B.
      
 0.493
PCDH18
Protocadherin 18.
    
 
 0.492
CAPN9
Calpain 9; Belongs to the peptidase C2 family.
      
 0.486
ADAM30
ADAM metallopeptidase domain 30.
    
 
 0.472
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.