STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif 8. (896 aa)    
Predicted Functional Partners:
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4.
   
 
 0.704
BCAN
Uncharacterized protein.
    
 
 0.692
TMEM8A
Transmembrane protein 8A.
      
 0.690
ATOH7
Atonal bHLH transcription factor 7.
      
 0.594
MMP11
Matrix metallopeptidase 11.
    
 
 0.594
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
      
 0.549
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12.
   
 
 0.537
HSF2
Heat shock transcription factor 2.
      
 0.535
RPAP3
RNA polymerase II associated protein 3.
      
 0.518
ANXA1
Annexin.
      
 0.472
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.