STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif 8. (896 aa)    
Predicted Functional Partners:
TMEM8A
Transmembrane protein 8A.
      
 0.713
HAPLN4
Hyaluronan and proteoglycan link protein 4.
      
 0.664
BCAN
Uncharacterized protein.
      
 0.644
HSF2
Heat shock transcription factor 2.
      
 0.564
RPAP3
RNA polymerase II associated protein 3.
      
 0.560
TSKU
Tsukushi, small leucine rich proteoglycan.
      
 0.515
EPDR1
Ependymin related 1.
      
 0.506
CARD10
Caspase recruitment domain family member 10.
    
 
 0.505
LECT2
Leukocyte cell derived chemotaxin 2.
      
 0.502
HAPLN2
Hyaluronan and proteoglycan link protein 2.
      
 0.491
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.