TBR1 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

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Score

TBR1

T-box brain transcription factor 1. (682 aa)

Predicted Functional Partners:

SATB2

0.961

NES

0.831

DLX2

0.830

CUX1

0.808

GFAP

0.786

FEZF2

0.779

FOXP2

0.748

OLIG2

0.732

SOX5

0.731

BCL11B

0.721

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL11B	CUX1	ENSCAFP00000026270	ENSCAFP00000062672	BAF chromatin remodeling complex subunit BCL11B.	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	0.527
BCL11B	DLX2	ENSCAFP00000026270	ENSCAFP00000031627	BAF chromatin remodeling complex subunit BCL11B.	Distal-less homeobox 2.	0.462
BCL11B	SATB2	ENSCAFP00000026270	ENSCAFP00000036183	BAF chromatin remodeling complex subunit BCL11B.	DNA-binding protein SATB.	0.754
BCL11B	TBR1	ENSCAFP00000026270	ENSCAFP00000014694	BAF chromatin remodeling complex subunit BCL11B.	T-box brain transcription factor 1.	0.721
CUX1	BCL11B	ENSCAFP00000062672	ENSCAFP00000026270	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	BAF chromatin remodeling complex subunit BCL11B.	0.527
CUX1	FEZF2	ENSCAFP00000062672	ENSCAFP00000010567	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	FEZ family zinc finger 2.	0.670
CUX1	FOXP2	ENSCAFP00000062672	ENSCAFP00000047072	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Forkhead box P2.	0.667
CUX1	GFAP	ENSCAFP00000062672	ENSCAFP00000058935	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.677
CUX1	NES	ENSCAFP00000062672	ENSCAFP00000024660	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Nestin; Belongs to the intermediate filament family.	0.680
CUX1	OLIG2	ENSCAFP00000062672	ENSCAFP00000041269	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Oligodendrocyte transcription factor 2.	0.405
CUX1	SATB2	ENSCAFP00000062672	ENSCAFP00000036183	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	DNA-binding protein SATB.	0.891
CUX1	SOX5	ENSCAFP00000062672	ENSCAFP00000017109	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	SRY-box 5.	0.642
CUX1	TBR1	ENSCAFP00000062672	ENSCAFP00000014694	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	T-box brain transcription factor 1.	0.808
DLX2	BCL11B	ENSCAFP00000031627	ENSCAFP00000026270	Distal-less homeobox 2.	BAF chromatin remodeling complex subunit BCL11B.	0.462
DLX2	FEZF2	ENSCAFP00000031627	ENSCAFP00000010567	Distal-less homeobox 2.	FEZ family zinc finger 2.	0.668
DLX2	GFAP	ENSCAFP00000031627	ENSCAFP00000058935	Distal-less homeobox 2.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.467
DLX2	NES	ENSCAFP00000031627	ENSCAFP00000024660	Distal-less homeobox 2.	Nestin; Belongs to the intermediate filament family.	0.572
DLX2	OLIG2	ENSCAFP00000031627	ENSCAFP00000041269	Distal-less homeobox 2.	Oligodendrocyte transcription factor 2.	0.571
DLX2	SATB2	ENSCAFP00000031627	ENSCAFP00000036183	Distal-less homeobox 2.	DNA-binding protein SATB.	0.703
DLX2	SOX5	ENSCAFP00000031627	ENSCAFP00000017109	Distal-less homeobox 2.	SRY-box 5.	0.501