STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATOH1Atonal bHLH transcription factor 1. (356 aa)    
Predicted Functional Partners:
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.818
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.742
TCF12
Transcription factor 12.
    
 
 0.741
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
      
 0.735
POU4F3
POU domain protein.
    
 
 0.734
TCF4
Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3') (By similarity). Binds to the thyroglobulin promoter.
    
 
 0.674
TCF3
Transcription factor 3.
    
 
 0.674
BARHL1
BarH like homeobox 1.
   
 
 0.673
HES5
Hes family bHLH transcription factor 5.
    
 
 0.666
PHOX2B
Paired like homeobox 2B.
      
 0.664
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.