LONP2 protein (Canis lupus familiaris) - STRING interaction network

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LONP2

Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)

Predicted Functional Partners:

CLPX

0.914

CLPP

0.840

PEX5

0.784

PIPOX

0.760

GRPEL1

0.738

HAO2

0.737

DDO

0.718

CLPB

0.718

ACOT8

0.715

GNPAT

0.709

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT8	DDO	ENSCAFP00000038062	ENSCAFP00000005787	Acyl-CoA thioesterase 8.	D-aspartate oxidase.	0.652
ACOT8	GNPAT	ENSCAFP00000038062	ENSCAFP00000017416	Acyl-CoA thioesterase 8.	Dihydroxyacetone phosphate acyltransferase.	0.680
ACOT8	HAO2	ENSCAFP00000038062	ENSCAFP00000014757	Acyl-CoA thioesterase 8.	Hydroxyacid oxidase 2.	0.700
ACOT8	LONP2	ENSCAFP00000038062	ENSCAFP00000014765	Acyl-CoA thioesterase 8.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.715
ACOT8	PEX5	ENSCAFP00000038062	ENSCAFP00000020745	Acyl-CoA thioesterase 8.	Peroxisomal biogenesis factor 5.	0.813
ACOT8	PIPOX	ENSCAFP00000038062	ENSCAFP00000027853	Acyl-CoA thioesterase 8.	Pipecolic acid and sarcosine oxidase.	0.711
CLPB	CLPP	ENSCAFP00000065447	ENSCAFP00000027588	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ATP-dependent Clp protease proteolytic subunit.	0.970
CLPB	CLPX	ENSCAFP00000065447	ENSCAFP00000063543	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	0.916
CLPB	GRPEL1	ENSCAFP00000065447	ENSCAFP00000054101	ClpB homolog, mitochondrial AAA ATPase chaperonin.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.929
CLPB	LONP2	ENSCAFP00000065447	ENSCAFP00000014765	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.718
CLPP	CLPB	ENSCAFP00000027588	ENSCAFP00000065447	ATP-dependent Clp protease proteolytic subunit.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.970
CLPP	CLPX	ENSCAFP00000027588	ENSCAFP00000063543	ATP-dependent Clp protease proteolytic subunit.	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	0.999
CLPP	GRPEL1	ENSCAFP00000027588	ENSCAFP00000054101	ATP-dependent Clp protease proteolytic subunit.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.671
CLPP	LONP2	ENSCAFP00000027588	ENSCAFP00000014765	ATP-dependent Clp protease proteolytic subunit.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.840
CLPX	CLPB	ENSCAFP00000063543	ENSCAFP00000065447	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.916
CLPX	CLPP	ENSCAFP00000063543	ENSCAFP00000027588	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	ATP-dependent Clp protease proteolytic subunit.	0.999
CLPX	GRPEL1	ENSCAFP00000063543	ENSCAFP00000054101	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.542
CLPX	LONP2	ENSCAFP00000063543	ENSCAFP00000014765	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.914
DDO	ACOT8	ENSCAFP00000005787	ENSCAFP00000038062	D-aspartate oxidase.	Acyl-CoA thioesterase 8.	0.652
DDO	GNPAT	ENSCAFP00000005787	ENSCAFP00000017416	D-aspartate oxidase.	Dihydroxyacetone phosphate acyltransferase.	0.595

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