STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)    
Predicted Functional Partners:
CLPX
Caseinolytic mitochondrial matrix peptidase chaperone subunit.
 
 
 0.968
CLPP
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.838
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.804
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.799
CRBN
Cereblon.
   
  
 0.761
UBOX5
U-box domain containing 5.
   
  
 0.709
RANGRF
RAN guanine nucleotide release factor.
      
 0.702
PDZRN3
PDZ domain containing ring finger 3.
      
 0.702
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
  
 
 0.701
FCHSD2
FCH and double SH3 domains 2.
      
 0.700
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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