STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC8AKelch domain containing 8A. (350 aa)    
Predicted Functional Partners:
TMEM71
Transmembrane protein 71.
      
 0.676
CCDC18
Coiled-coil domain containing 18.
      
 0.653
RAB42
RAB42, member RAS oncogene family.
   
  
 0.592
GAS2L3
Growth arrest specific 2 like 3.
   
  
 0.534
PEX7
Peroxisomal biogenesis factor 7.
    
   0.528
KLHDC4
Kelch domain containing 4.
      
 0.489
KLHL9-2
Uncharacterized protein.
  
 
   0.485
LAMP3
Uncharacterized protein.
      
 0.457
KRT23
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.450
GMPPA
GDP-mannose pyrophosphorylase A.
   
  
 0.450
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.