STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC8AKelch domain containing 8A. (350 aa)    
Predicted Functional Partners:
PEX7
Peroxisomal biogenesis factor 7.
    
   0.833
TXNDC9
Thioredoxin domain containing 9.
    
   0.813
CCT5
Chaperonin containing TCP1 subunit 5.
    
   0.770
PDCL
Phosducin like.
    
   0.769
CCT3
T-complex protein 1 subunit gamma.
    
 
 0.617
CCT8L2
Chaperonin containing TCP1 subunit 8 like 2.
    
   0.564
CCT8
Chaperonin containing TCP1 subunit 8.
    
   0.564
KLHL9-2
Uncharacterized protein.
  
 
  0.513
PDC
Phosducin; Inhibits the transcriptional activation activity of the cone- rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism.
    
   0.510
CCT7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
   0.454
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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