STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQCF1IQ motif containing F1. (207 aa)    
Predicted Functional Partners:
HMGB4
High mobility group box 4.
   
 
 0.714
CCDC181
Coiled-coil domain containing 181.
      
 0.709
ANKRD9
Ankyrin repeat domain 9.
      
 0.706
RASSF3
Ras association domain family member 3.
      
 0.705
CNBD2
Cyclic nucleotide binding domain containing 2.
   
  
 0.629
KLHL10
Kelch like family member 10.
   
  
 0.568
MFSD14A
Major facilitator superfamily domain containing 14A.
      
 0.562
KLHDC3
Kelch domain containing 3.
      
 0.560
CCDC182
Coiled-coil domain containing 182.
   
  
 0.545
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
   
  
 0.538
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.