STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCC11ATP binding cassette subfamily C member 11. (1384 aa)    
Predicted Functional Partners:
ABCC6
ATP binding cassette subfamily C member 6.
  
  
0.674
ABCC1
Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (By similarity). Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). [...]
  
  
0.649
ABCC3
ATP binding cassette subfamily C member 3.
  
  
0.648
ABCA7
ATP binding cassette subfamily A member 7.
    
 0.646
ABCF3
ATP binding cassette subfamily F member 3.
   
 0.581
ABCG4
ATP binding cassette subfamily G member 4.
   
 0.558
SLC10A1
Solute carrier family 10 member 1.
   
  
 0.556
ZCCHC9
Zinc finger CCHC-type containing 9.
    
 
 0.533
cOR13P3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.532
ABCF1
ATP binding cassette subfamily F member 1.
   
 0.524
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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