STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNNI2Troponin I2, fast skeletal type. (182 aa)    
Predicted Functional Partners:
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle.
   
 0.982
TNNT3
Troponin T3, fast skeletal type.
   
 0.979
ATP2A1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.977
TNNC1
Troponin C1, slow skeletal and cardiac type.
   
 0.976
TNNT1
Troponin T1, slow skeletal type.
   
 0.972
MYL1
Myosin light chain 1.
   
 0.952
MYOZ1
Calsarcin 2.
   
  
 0.950
TNNT2
Troponin T2, cardiac type.
 
 
 0.936
TNNI3
Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  
 
0.924
ACTN3
Actinin alpha 3.
   
 0.918
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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