STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSP1Lymphocyte specific protein 1. (368 aa)    
Predicted Functional Partners:
KSR1
Kinase suppressor of ras 1.
   
 0.929
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 
 0.910
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
     
 0.909
ARHGEF12
Rho guanine nucleotide exchange factor 12.
     
 0.902
CD209
C-type lectin domain-containing protein.
   
 0.902
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
     
  0.900
PLK3
Serine/threonine-protein kinase PLK.
   
 
 0.831
TOX3
TOX high mobility group box family member 3.
      
 0.827
EBAG9
Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
      
 0.803
TMEM128
Transmembrane protein 128.
      
 0.712
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.