STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK18Cyclin dependent kinase 18; Belongs to the protein kinase superfamily. (436 aa)    
Predicted Functional Partners:
CKS1B
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 
 0.684
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.656
FAM189A2
Family with sequence similarity 189 member A2.
   
  
 0.652
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.586
INTU
Inturned planar cell polarity protein.
   
 
 0.584
CDC20B
Cell division cycle 20B.
   
 
 0.584
CDC20
Cell division cycle 20.
   
 
 0.584
CCNK
Cyclin K; Belongs to the cyclin family.
   
 
 0.580
ORC2
Origin recognition complex subunit 2.
 
 
 
 0.578
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.