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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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THTyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons. (495 aa)    
Predicted Functional Partners:
DDC
Dopa decarboxylase.
   
 0.979
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
 0.979
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.952
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
  
 0.952
DBH
Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.
   
  
 0.947
QDPR
Quinoid dihydropteridine reductase.
  
 
 0.941
SPR
Sepiapterin reductase.
   
 
 0.930
TYR
Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. Belongs to the tyrosinase family.
   
 
 0.919
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.916
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
  
 
 0.915
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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