STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHCHD2Coiled-coil-helix-coiled-coil-helix domain containing 2. (152 aa)    
Predicted Functional Partners:
SUMF2
Sulfatase modifying factor 2.
      
 0.825
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
      
 0.805
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
      
 0.709
PHKG1
Phosphorylase kinase catalytic subunit gamma 1.
 
    
 0.701
CHCHD3
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 
 0.698
AK4
DnaJ heat shock protein family (Hsp40) member C6.
      
 0.674
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13.
   
  
 0.673
TARDBP
TAR DNA binding protein.
   
 0.668
ENSCAFP00000048491
RRM domain-containing protein.
   
 0.668
ATP13A2
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.661
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.