STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEKDEK proto-oncogene. (344 aa)    
Predicted Functional Partners:
BAZ1B
Bromodomain adjacent to zinc finger domain 1B.
   
 0.846
UPF1
UPF1 RNA helicase and ATPase.
    
 
 0.813
TFAP2A
Transcription factor AP-2 alpha.
    
 0.731
THUMPD2
THUMP domain containing 2.
      
 0.718
SPOP
Speckle type BTB/POZ protein.
    
 
 0.679
RBM27
Uncharacterized protein.
      
 0.676
MYBBP1A
MYB binding protein 1a.
    
 0.650
DAXX
Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]
    
 
 0.649
RSBN1
Round spermatid basic protein 1.
   
  
 0.644
SPOPL
Speckle type BTB/POZ protein like.
    
 
 0.642
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.