STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEKDEK proto-oncogene. (344 aa)    
Predicted Functional Partners:
BAZ1B
Bromodomain adjacent to zinc finger domain 1B.
    
 0.867
SF3B1
Splicing factor 3b subunit 1.
   
 
 0.860
MYBBP1A
MYB binding protein 1a.
     
 0.855
DDX21
DExD-box helicase 21.
     
 0.846
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
   
 0.834
UPF1
UPF1 RNA helicase and ATPase.
    
 
 0.826
MYO1C
Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.803
TFAP2A
Transcription factor AP-2 alpha.
    
 0.745
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.643
SPOP
Speckle type BTB/POZ protein.
    
 
 0.603
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.