STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB29RAB29, member RAS oncogene family. (203 aa)    
Predicted Functional Partners:
NUCKS1
Nuclear casein kinase and cyclin dependent kinase substrate 1.
 
    
 0.851
RILPL2
Rab interacting lysosomal protein like 2.
      
 0.846
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.841
RILPL1
Rab interacting lysosomal protein like 1.
      
 0.834
PPM1H
Protein phosphatase, Mg2+/Mn2+ dependent 1H.
    
 
 0.783
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.748
LRRK2
Leucine rich repeat kinase 2.
    
 
 0.725
AAMP
Angio-associated migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway (By similarity).
      
 0.669
PPM1M
Protein phosphatase, Mg2+/Mn2+ dependent 1M.
    
 
 0.630
RAB3IP
RAB3A interacting protein.
      
 0.615
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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