STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF1DDB1 and CUL4 associated factor 1. (1506 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.998
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.996
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.990
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
    
 
 0.959
NF2
Neurofibromin 2.
    
 
 0.946
DDA1
DET1 and DDB1 associated 1.
    
 
 0.938
COPS5
COP9 signalosome subunit 5.
    
 
 0.928
RBX1
Ring-box 1.
    
 
 0.880
COPS6
COP9 signalosome subunit 6.
    
 
 0.842
COPS3
COP9 signalosome subunit 3.
    
 
 0.834
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.