STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF1DDB1 and CUL4 associated factor 1. (1506 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.999
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.997
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.989
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
    
 
 0.974
RBX1
Ring-box 1.
    
 
 0.925
KPNA5
Importin subunit alpha; Functions in nuclear protein import.
      
 0.795
ENSCAFP00000053494
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
    
 
 0.776
UNG
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
    
 
 0.776
NF2
Neurofibromin 2.
    
 
 0.731
DDA1
DET1 and DDB1 associated 1.
    
 
 0.720
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.