STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUEDC2CUE domain containing 2. (383 aa)    
Predicted Functional Partners:
CRYBG3
Crystallin beta-gamma domain containing 3; Belongs to the beta/gamma-crystallin family.
      
 0.848
MYNN
Myoneurin.
      
 0.769
PREPL
Prolyl endopeptidase like.
   
  
 0.679
CUEDC1
CUE domain containing 1.
      
 0.678
FBXL15
F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity); Belongs to the FBXL15 family.
   
  
 0.674
FAM110B
Family with sequence similarity 110 member B.
      
 0.671
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
  
 0.654
WDR75
WD repeat domain 75.
   
  
 0.649
MFSD13A
Major facilitator superfamily domain containing 13A.
      
 0.649
TRIM8
Tripartite motif containing 8.
   
  
 0.649
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.