STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUEDC2CUE domain containing 2. (383 aa)    
Predicted Functional Partners:
CRYBG3
Crystallin beta-gamma domain containing 3; Belongs to the beta/gamma-crystallin family.
      
 0.827
FZR1
Fizzy and cell division cycle 20 related 1.
    
 
 0.773
FBXL15
F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity); Belongs to the FBXL15 family.
   
  
 0.697
TBPL2
TATA-box binding protein like 2.
   
   0.695
TBP
TATA-box binding protein.
   
   0.695
MYNN
Myoneurin.
      
 0.692
WDR75
WD repeat domain 75.
      
 0.690
MFSD13A
Major facilitator superfamily domain containing 13A.
      
 0.690
NSMAF
Neutral sphingomyelinase activation associated factor.
      
 0.689
CDC27
Cell division cycle 27.
    
 
 0.681
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.