STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)    
Predicted Functional Partners:
SGK1
Non-specific serine/threonine protein kinase.
     
 0.926
SLC12A3
Solute carrier family 12 member 3.
   
  
 0.817
BSND
Barttin CLCNK type accessory beta subunit.
   
  
 0.786
MIOX
Myo-inositol oxygenase.
   
  
 0.732
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.667
SCNN1A
Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.634
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.629
AOC3
Amine oxidase copper containing 3.
   
 
 0.595
SLC12A1
Solute carrier family 12 member 1.
   
  
 0.584
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
   
  
 0.581
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.