STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISHCytokine inducible SH2 containing protein. (257 aa)    
Predicted Functional Partners:
STAT5A
Signal transducer and activator of transcription.
   
 0.936
STAT5B
Signal transducer and activator of transcription.
   
 0.935
STAT1
Signal transducer and activator of transcription.
   
 0.935
STAT3
Signal transducer and activator of transcription.
   
 0.932
STAT4
Signal transducer and activator of transcription.
   
 0.930
STAT2
Signal transducer and activator of transcription.
   
 0.920
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
   
 0.919
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.866
ELOB
Elongin B.
    
 0.861
ELOC
Elongin C; Belongs to the SKP1 family.
   
 0.783
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.