STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (842 aa)    
Predicted Functional Partners:
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
   
 
 0.920
ENSCAFP00000053146
Uncharacterized protein.
     
 0.798
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
     
 0.798
ALDH5A1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
  
 0.622
PON1
Paraoxonase 3.
   
  
 0.604
PON2
Serum paraoxonase/arylesterase 2; Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters; Belongs to the paraoxonase family.
   
  
 0.604
ALPL
Alkaline phosphatase.
     
 0.598
PDP2
Pyruvate dehyrogenase phosphatase catalytic subunit 2.
   
  
 0.596
PDP1
Pyruvate dehyrogenase phosphatase catalytic subunit 1.
      
 0.595
PPM1A
Protein phosphatase, Mg2+/Mn2+ dependent 1A.
      
 0.591
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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