STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA4PTPRF interacting protein alpha 4. (1202 aa)    
Predicted Functional Partners:
PCDHA13
Protocadherin alpha 13.
    
 
 0.853
PKP4
Plakophilin 4.
   
  
 0.775
ZNF638
Zinc finger protein 638.
    
 
 0.751
PTPRF
Protein tyrosine phosphatase receptor type F.
    
 0.710
CNTFR
Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).
      
 0.609
GRM8
Glutamate metabotropic receptor 8.
   
  
 0.602
GRM7
Glutamate metabotropic receptor 7.
   
  
 0.600
ERC2
ELKS/RAB6-interacting/CAST family member 2.
   
 
 0.588
ERC1
ELKS/RAB6-interacting/CAST family member 1.
   
 
 0.583
PPFIBP2
PPFIA binding protein 2.
   
0.555
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.