STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA4PTPRF interacting protein alpha 4. (1202 aa)    
Predicted Functional Partners:
PCDHA13
Protocadherin alpha 13.
    
 
 0.815
PKP4
Plakophilin 4.
   
  
 0.789
PPFIBP2
PPFIA binding protein 2.
   
0.721
PPFIBP1
PPFIA binding protein 1.
   
0.721
ZNF638
Zinc finger protein 638.
    
 
 0.692
ZNF831
Zinc finger protein 831.
      
 0.682
PTPRF
Protein tyrosine phosphatase receptor type F.
    
 0.663
PTPRD
Protein tyrosine phosphatase receptor type D.
   
 0.661
GRM8
Glutamate metabotropic receptor 8.
   
  
 0.645
CNTFR
Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).
      
 0.644
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.